TRETIN 0.025% / 0.05% TRETINOIN CREAM | 30g/1.06oz

Properties and indications:

• Tretin® cream tretinoin in a concentration of 0.025% / 0.05% (refers to the retinoid class);
• inhibits compound pathogenic cells that form acne, so is used to treat acne and comedones;
• reduces different manifestations of hyperpigmentation, such as acne spots, age spots, freckles, and others;
• has anti-aging, regenerative, anti-seborrhoeic, anti-inflammatory, keratolytic, and immunostimulatory effects;
• when treatment opens blackheads help equalize the skin surface;
• when processing closed blackheads helps them open or transition to the papules, followed by healing (no scarring);
• best suited for dry skin;
• the best time for the application – is autumn-winter.

The composition and release form:

cream for external use 30g/1.06oz

Active ingredient:

tretinoin USP – 0.025% / 0.05% w/w in a cream base q.s.

Preservatives:

• sorbic acid IP – 0.20 % w/w;
• butylated hydroxytoluene IP – 0.10 % w/w adequate overage addet.

Contraindications:

• children under 12 years;
• pregnancy;
• lactation;
• acute inflammation (including eczema) lesions of the skin (dermatitis, seborrhea, and others);
• rosacea;
• skin lesions (wounds, burns, etc.);
• photosensitivity;
• diseases of the rectum;
• hypersensitivity to any component of the cream (discontinue use and consult a doctor if you have any of these signs of an allergic reaction: hives, difficulty breathing, swelling of the face, lips, tongue, or throat).

Side effects of the preparation

Frequently: reaches a peak within the first week of treatment, and then spontaneously go - scaling, dryness, burning, redness; increased sensitivity to sunlight and UV rays;

Rarely (in 5-12% of cases): erythema, itching, temporary hyperpigmentation, and hypopigmentation (possible with multiple applications of tretinoin);

Rarely (in 1-2% of cases): allergic contact dermatitis.

Dosage and how to use:

• apply the cleanser;
• wait until complete drying of the skin (30 minutes);
• topically applied a thin layer on the entire affected surface 1 time day in the evening, avoiding contact with the eyes and mucous membrane of the lips. Later may be applied 1-2 times a day for 1-6 hours and then washed off with warm water;
• for people with fair and dry skin exposure time at the beginning of the treatment is 30 minutes, then the duration of exposure can be gradually increased;
• after necessary to wash your hands;
• avoid the use of other products on the treated areas (at least 1 hour after application of tretinoin);
• if there is dry (after an hour of applying the cream), apply a moisturizer;
• the result will be seen after 1-4 weeks of treatment;
• treatment time – 3-4 months. Retreatment after consultation with a physician.

Special instructions:

• do not use if you have wounds, burns, or symptoms of eczema, dermatitis, or rosacea;
• do not use it if you are allergic to any of the ingredients of the drug. If any of the symptoms of allergy - contact your doctor immediately;
• do not use it for a week or two after the irritating procedures (peels, hair removal, etc.);
• the use of excessive amounts does not give rapid effect, but on the contrary, can make the skin more irritable and dry;
• may use non-comedogenic cosmetics, but the area where it was applied, should be thoroughly cleaned;
• transient sense of warmth and a slight burning sensation may be noted after application;
• excessive dryness of the skin after Tretin cream is a sign that we should reduce the frequency of applications, and possibly the numbers. If this does not work, apply the cream for 5-40 minutes and rinse with water. Your skin should gradually adapt to it. Also if there are dry, it is necessary to use moisturizer for better therapy;
• people with hypersensitivity to the sun should exercise particular caution. When applied topically should protect skin from exposure to sunlight and artificial UV exposure, wind, and cold;
• having a tan, treatment should begin after the weakening of tanning;
• in contact with mucous membranes of the mouth, rinse with water;
• do not use with products that have irritation or desiccating properties (for example, sulfur, resorcinol, salicylic acid, containing alcohol, and others.). Avoid contact with the peel of lime;
• in the early weeks of therapy, may occur exacerbation of inflammatory lesions, but this should not be considered as a reason to discontinue therapy.

Storage conditions:

• at a temperature not exceeding 25 °C;
• do not freeze;
• keep out of the reach of children;
• highly flammable - keep the tube away from open flame.

Shelf life:

24 months